Author

S. Jirde

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Das· 1 shared C. N. Butterfield· 1 shared C. T. Brown· 1 shared D. S. Goltsman· 1 shared D. W. Taylor· 1 shared I. Noceda· 1 shared J. P. Bravo· 1 shared K. A. Johnson· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Das

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1 paper

Recent·Most cited

DNA targeting by compact Cas9d and its resurrected ancestor

R. Fregoso Ocampo, J. P. Bravo, T. L. Dangerfield, I. Noceda, S. Jirde, L. M. Alexander, A. Das, S. Nielsen, K. A. Johnson, C. T. Brown, C. N. Butterfield, D. S. Goltsman, D. W. Taylor

This study reports cryo-EM structures of Cas9d, revealing its DNA targeting mechanism and demonstrating a compact variant with robust nuclease activity in mammalian cells.

bioRxiv · Apr 8, 2024 · PreprintBiochemistry