Tristetraprolin prevents gastric metaplasia in mice by suppressing pathogenic inflammation
J. T. Busada, S. Kadka, K. N. Peterson, D. J. Stumpo, L. Zhou, J. A. Cidlowski, P. J. Blackshear
This study shows that TTP overexpression prevents gastric inflammation and metaplasia in mice by suppressing innate immune genes, with partial protection linked to Tnf suppression.
bioRxiv · Jan 21, 2021Immunology