Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms
M. Selvaraj, S. Kokate, G. Reggiano, K. Kogan, T. Kotila, E. Kremneva, F. DiMaio, P. Lappalainen, J. T. Huiskonen
The paper determines cryo-EM structures of actin filaments with two non-muscle tropomyosin isoforms, revealing structural differences that explain their distinct functional roles.
bioRxiv · May 12, 2022Biochemistry