Author

T. Kotila

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

P. Lappalainen· 3 shared K. Kogan· 2 shared A. Colin· 1 shared A. Michelot· 1 shared A. Mogilner· 1 shared A. Vizcaino-Castillo· 1 shared B. Vianay· 1 shared C. Guerin· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

P. Lappalainen

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Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJan 6, 2023

Unusual actin-binding mechanism and the role of profilin in actin dynamics of trypanosomatid parasites

A. Vizcaino-Castillo, T. Kotila, K. Kogan…·P. Lappalainen

This study identifies a unique actin-binding mechanism of profilin in trypanosomatid parasites, revealing its role in actin dynamics and potential as a drug target.

DOI 10.1101/2023.01.06.522972

humanexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintSep 30, 2022

Recycling limits the lifetime of actin turnover

A. Colin, T. Kotila, C. Guerin…·L. Blanchoin

This study investigates how actin turnover is sustained with a limited monomer pool by analyzing bead motility and identifying recycling as a key factor.

DOI 10.1101/2022.09.30.510257

experimental assaycell signaling & trafficking

𝕏 PostBluesky

BiochemistrybioRxivMay 12, 2022

Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms

M. Selvaraj, S. Kokate, G. Reggiano…·J. T. Huiskonen

The paper determines cryo-EM structures of actin filaments with two non-muscle tropomyosin isoforms, revealing structural differences that explain their distinct functional roles.

DOI 10.1016/j.celrep.2022.111900

cryo-EMexperimental assay

𝕏 PostBluesky