Trade-offs constrain adaptive pathways to T6 survival
K. A. MacGillivray, S. L. Ng, S. Wiesenfeld, R. L. Guest, T. Jubery, T. J. Silhavy, W. C. Ratcliff, B. K. Hammer
This study uses experimental evolution to show that Escherichia coli evolves resistance to Vibrio cholerae's Type VI Secretion System (T6) through specific mutations, but these mutations come with fitness costs.
bioRxiv · Sep 2, 2022Evolutionary Biology