Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing.
N. F. H. N. van Bree, A.-S. Oppelt, S. Lindstrom, L. Zhou, L. Boutin, J. I. Johnsen, L. Brautigam, M. T. Wilhelm
This paper develops a zebrafish model for medulloblastoma drug testing, showing that neural stem cell culture conditions enhance tumor cell homing and aggressiveness, enabling high-throughput screening.
bioRxiv · Feb 21, 2024Cancer Biology