Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
K. M. MacDonald, S. Khan, T. M. Kislinger, S. M. Harding
The paper profiles the proteome of micronuclei, cytoplasm, and nuclei in human cells exposed to genotoxins, revealing distinct proteomic features and their implications for DNA damage and chromothripsis.
K. M. MacDonald, S. Nicholson-Puthenveedu, M. M. Tageldein…·S. M. Harding
The paper shows that cGAS recruitment to micronuclei depends on pre-existing nuclear chromatin status, not just MN envelope rupture.
R. A. Greenberg, J. Chen, S. M. Harding…·I. Asangani
The paper shows that disrupting cell cycle checkpoints can restore DNA damage-induced inflammation and anti-tumor immune responses in cancer cells.
S. M. Harding, J. L. Benci, J. Irianto…·R. A. Greenberg
The paper shows that mitotic progression after DNA damage forms micronuclei, which activate inflammatory signaling and are critical for abscopal tumor regression in combination with immune checkpoint blockade.