R. A. Greenberg

This study identifies ALC1 as a key determinant of PARPi toxicity in HR-deficient cells by linking PARP-dependent chromatin remodeling to PARPi response.

The paper shows that disrupting cell cycle checkpoints can restore DNA damage-induced inflammation and anti-tumor immune responses in cancer cells.

The paper investigates how Peromyscus mice adapt their burrowing behavior when digging individually versus with partners, finding that cooperative digging results in longer burrows due to increased social cohesion in opposite-sex pairs.

The paper shows that APBs function as liquid condensates that cluster telomeres through liquid properties, supporting the ALT pathway in telomerase-free cancer cells.

The paper investigates DNA damage and cell cycle effects during constricted cell migration, finding a bimodal relationship between DNA damage and cell cycle regulation.

The paper shows that mitotic progression after DNA damage forms micronuclei, which activate inflammatory signaling and are critical for abscopal tumor regression in combination with immune checkpoint blockade.