S. Macedo-Ribeiro

This study shows that transthyretin (TTR) selectively proteolyzes specific conformations of alpha-synuclein (aSyn), preventing its aggregation, with implications for neurodegenerative diseases.

The paper derives a kinetic solution to predict biological condensate formation by considering surface tension and nucleation-growth rates, showing large condensates can form without size control mechanisms.

This study identifies unique structural features of CaRas1 and its activation by CaCdc25 in Candida albicans, revealing potential targets for antifungal therapies.

This study identifies CLASP2's role in stabilizing kinetochore microtubule attachments through lattice-binding near microtubule plus ends, ensuring accurate chromosome segregation.

The paper identifies a novel glucosamine kinase family in Actinobacteria through structural and biochemical analysis, revealing a specific binding motif and potential role in antibiotic biosynthesis.