Author

S. Maisel

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. L. Swaney· 1 shared G. K. L. Chan· 1 shared H. L. Kenerson· 1 shared J. D. Gordan· 1 shared J. D. Scott· 1 shared K. C. Patra· 1 shared K. J. Riehle· 1 shared M. Bouhaddou· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

D. L. Swaney

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1 paper

Recent·Most cited

Oncogenic PKA signaling stabilizes MYC oncoproteins via an aurora kinase A-dependent mechanism

G. K. L. Chan, S. Maisel, Y. C. Hwang, R. R. B. Wolber, P. Vu, K. C. Patra, M. Bouhaddou, H. L. Kenerson, R. S. Yeung, D. L. Swaney, N. J. Krogan, R. E. Turnham, J. D. Scott, K. J. Riehle, N. Bardeesy, J. D. Gordan

This study identifies two PKA-driven oncogenic mechanisms, showing AURKA stabilizes MYC oncoproteins through a PIM2-mediated feedback loop, and suggests CD-532 as a potential therapeutic target.

bioRxiv · Apr 16, 2021Cancer Biology