Scalable production of tissue-like vascularised liver organoids from human PSCs.
S. P. Harrison, R. Sillar, Y. Tanaka, Y. Xiang, B. Patterson, H. Kempf, E. Melum, K. Asrud, M. E. Chollet, E. Andersen, P. M. Sandset, S. Baumgarten, F. Bonanini, D. Kurek, S. Mathapati, , G. J. Sullivan
This paper develops a method to produce vascularised liver organoids from human PSCs without 2D patterning or ECM, demonstrating liver-like functions and cellular complexity.
bioRxiv · Dec 2, 2020 · PreprintCell Biology