Metallothionein 3-zinc axis suppresses caspase-11 inflammasome activation and impairs antibacterial immunity
D. Chowdhury, J. Gardner, A. Satpati, S. Nookala, S. Mukundan, A. Porollo, J. Landero Figueroa, K. Subramanian
The paper identifies MT3 as a negative regulator of caspase-11 inflammasome activation in macrophages, which suppresses antibacterial immunity.
bioRxiv · Jul 28, 2021Immunology