Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD
J. A. Engel, H. J. Lee, C. G. Williams, R. Kuns, S. Olver, L. I. M. Lansink, M. S. F. Soon, S. B. Andersen, J. E. Powell, V. Svensson, S. A. Teichmann, G. R. Hill, A. Varelias, M. Koyama, A. Haque
This study uses single-cell RNA sequencing to track the differentiation of allo-reactive CD4+ T cells during gut GVHD, revealing divergent fates into quiescent and effector states.
bioRxiv · Mar 8, 2020Immunology