C. G. Williams

This study examines CD4+ T cell recall dynamics during Plasmodium re-infection in mice, revealing a spectrum of responses including refractory GC Tfh cells, rapid Th1-memory responses, and a partial facsimile of primary Th1 responses.

This paper uses spatial transcriptomics to map CD4+ T cell and B cell interactions in the spleen during malaria infection, revealing their localization and molecular requirements for immunity.

The paper shows that systemic host inflammation slows malaria parasite maturation and alters their transcriptomic profile in vivo.

This study identifies ADAR1-mediated editing of filovirus 3UTRs as negative regulators of translation, showing that editing or deletion enhances translation and modulates immune responses.

This study shows that pulsed broad-spectrum UV light inactivates SARS-CoV-2 on plastic, glass, stainless steel, and N95 respirators at specific UV doses.

This study identifies non-canonical proline-tyrosine interactions in the Ebola virus VP30 protein that regulate viral replication by interacting with multiple host proteins.

This study uses single-cell RNA sequencing to track the differentiation of allo-reactive CD4+ T cells during gut GVHD, revealing divergent fates into quiescent and effector states.

This paper compares MLAV viral proteins to EBOV and MARV homologs in their ability to modulate innate immune pathways in human and bat cells, identifying similarities and differences in IFN suppression mechanisms.

This study uses single-cell RNA-seq and ATAC-seq to show a progressive transition from effector to memory CD4+ T cells during Plasmodium infection, with linear pathways and memory-associated gene expression.