A. Haque

CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites.

This study examines CD4+ T cell recall dynamics during Plasmodium re-infection in mice, revealing a spectrum of responses including refractory GC Tfh cells, rapid Th1-memory responses, and a partial facsimile of primary Th1 responses.

Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria.

This paper uses spatial transcriptomics to map CD4+ T cell and B cell interactions in the spleen during malaria infection, revealing their localization and molecular requirements for immunity.

Bacterial communities associated with the surfaces of the fresh fruits sold around Dhaka Medical College and Hospital and their anti-microbial profiles

This study examines bacterial contamination on fresh fruits sold near a hospital in Bangladesh and identifies antimicrobial resistance genes among isolated pathogens.

Bladder-draining lymph nodes support germinal centre B cell responses during urinary tract infection in mice

This study shows that bladder-draining lymph nodes in mice develop germinal centre B cell responses during urinary tract infection, which may help control infection but are not enhanced by a second infection.

Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites

The paper shows that systemic host inflammation slows malaria parasite maturation and alters their transcriptomic profile in vivo.

Th2-like T-follicular helper cells promote functional antibody production during Plasmodium falciparum infection

The paper identifies Th2-like T-follicular helper cells as key drivers of functional antibody production during Plasmodium falciparum infection, suggesting they are targets for improved malaria vaccines.

Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD

This study uses single-cell RNA sequencing to track the differentiation of allo-reactive CD4+ T cells during gut GVHD, revealing divergent fates into quiescent and effector states.

Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells.

This study uses single-cell RNA-seq and ATAC-seq to show a progressive transition from effector to memory CD4+ T cells during Plasmodium infection, with linear pathways and memory-associated gene expression.