Differential Binding Kinetics for Evaluating Immune Checkpoint Inhibitors in Serum
S. X. Wang, K. Choudhury, D. Yao, H. Yu, A. Kantor, S. Osterfeld, T. Saito, M. L. Carbonell
This study measures binding kinetics of immune checkpoint inhibitors in serum using GMR biosensors and compares them to label-free methods, finding serum affects off-rates and pharmacological modeling.
bioRxiv · Aug 29, 2021 · PreprintBioengineering