S. Pasani

The molecular architecture of the desmosomal outer dense plaque by integrative structural modeling

This paper uses integrative structural modeling to determine the molecular architecture of the desmosomal outer dense plaque and identifies structural features related to mechanical stress resilience and disease.

Hybrid E/M phenotype(s) and stemness: a mechanistic connection embedded in network topology

This study develops a mathematical model to show hybrid epithelial/mesenchymal (E/M) phenotypes are more likely to acquire stemness than pure epithelial or mesenchymal states.