Author

S. Paz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. A. Burel· 2 shared S. P. Henry· 2 shared T. Machemer· 2 shared A. Fries· 1 shared A. J. Pollak· 1 shared B. Agan· 1 shared B. F. Baker· 1 shared C. B. Stauft· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPharmacology & Toxicology

S. A. Burel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antigenic cartography using hamster sera identifies SARS-CoV-2 JN.1 evasion seen in human XBB.1.5 booster sera

W. WANG, G. L. Bhushan, S. Paz, C. B. Stauft, P. Selvaraj, E. Goguet, K. A. Bishop-Lilly, R. Subramanian, R. Vassell, S. Lusvarghi, Y. Cong, B. Agan, S. A. Richard, N. Epsi, A. Fries, , C. D. Weiss

The paper uses hamster sera to map antigenic differences among SARS-CoV-2 variants, showing JN.1 has significant antigenic divergence from XBB.1.5.

bioRxiv · Apr 5, 2024 · PreprintMicrobiology

Mechanism Driven Early Stage Identification and Avoidance of Antisense Oligonucleotides Causing TRL9 Mediated Inflammatory Responses in Bjab cells

A. J. Pollak, P. Cauntay, T. Machemer, S. Paz, S. Damle, S. P. Henry, S. A. Burel

The paper develops and validates a high-throughput Bjab cell assay to identify proinflammatory PS-ASOs by measuring Ccl22 mRNA levels, showing it replicates hPBMC assay results and provides mechanistic insights.

bioRxiv · Dec 12, 2021 · PreprintPharmacology & Toxicology

Early-Stage Identification and Avoidance of Antisense Oligonucleotides Causing Species-Specific Inflammatory Responses in Human Volunteers Peripheral Blood Mononuclear Cells

S. A. Burel, T. Machemer, B. F. Baker, T. J. Kwoh, S. Paz, H. Younis, S. P. Henry

The paper develops a PBMC assay to identify ASOs causing immune responses in humans, finding variability in donor responses and linking IL-6 induction to TLR9 activation.

bioRxiv · Oct 30, 2021Pharmacology & Toxicology