Author

H. Younis

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Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. F. Baker· 1 shared S. A. Burel· 1 shared S. P. Henry· 1 shared S. Paz· 1 shared T. J. Kwoh· 1 shared T. Machemer· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. F. Baker

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivOct 30, 2021

Early-Stage Identification and Avoidance of Antisense Oligonucleotides Causing Species-Specific Inflammatory Responses in Human Volunteers Peripheral Blood Mononuclear Cells

S. A. Burel, T. Machemer, B. F. Baker…·S. P. Henry

The paper develops a PBMC assay to identify ASOs causing immune responses in humans, finding variability in donor responses and linking IL-6 induction to TLR9 activation.

DOI 10.1089/nat.2022.0033

humanbulk RNA-seq

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