BioengineeringbioRxiv
Programmable RNA detection with CRISPR-Cas12a
S. R. Rananaware, E. K. Vesco, G. M. Shoemaker…·P. K. Jain
This paper introduces SAHARA, a CRISPR-Cas12a-based method for direct RNA detection without reverse transcription, showing improved specificity and multiplexing capabilities.
DOI 10.1038/s41467-023-41006-1