Author

S. S. Shell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. C. Martini· 3 shared D. A. Vargas-Blanco· 2 shared H. Sun· 2 shared J. Xiao· 2 shared L. A. Roberts· 2 shared Y. Zhou· 2 shared C. Riva· 1 shared C. S. Masiello· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

M. C. Martini

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence

M. Bar-Oz, M. C. Martini, M. N. Alonso, M. Meir, N. I. Lore, P. Miotto, C. Riva, J. Xiao, C. S. Masiello, M.-A. Misiakou, H. Sun, J. K. Moy, H. K. Johansen, D. M. Cirillo, S. S. Shell, D. Barkan

This study identifies the sRNA B11 as a regulator of gene expression and virulence in Mycobacterium abscessus, showing it affects colony morphology, inflammation, antibiotic resistance, and secretion system activity.

bioRxiv · Oct 27, 2022 · PreprintMicrobiology

Teaching the Skills and Concepts of Gene Expression Analysis during COVID-19

L. A. Roberts, S. S. Shell

This study evaluates how remote learning affected student skill and concept acquisition in gene expression analysis during the pandemic, finding reduced skill gains but increased conceptual understanding.

bioRxiv · Jun 28, 2022 · PreprintScientific Communication & Education

Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis

M. C. Martini, N. D. Hicks, J. Xiao, T. Barbier, J. Sixsmith, S. M. Fortune, S. S. Shell

This study shows that loss of RNase J in Mtb leads to drug tolerance and accumulation of structured mRNA fragments, highlighting its role in RNA metabolism and drug resistance.

bioRxiv · Feb 13, 2022Microbiology

The impact of leadered and leaderless gene structures on translation efficiency, transcript stability, and predicted transcription rates in Mycobacterium smegmatis

T. G. Nguyen, D. A. Vargas-Blanco, L. A. Roberts, S. S. Shell

bioRxiv · Nov 29, 2019Microbiology

mRNA Degradation Rates Are Coupled to Metabolic Status in Mycobacteria

D. A. Vargas-Blanco, Y. Zhou, L. Gutierrez Zamalloa, T. Antonelli, S. S. Shell

This study shows that mRNA stability in mycobacteria is linked to metabolic status, not growth rate, as demonstrated by drug-induced changes in mRNA half-lives under growth arrest.

bioRxiv · Apr 1, 2019Microbiology

Defining the transcriptional and post-transcriptional landscapes of Mycobacterium smegmatis in aerobic growth and oxygen limitation

M. C. Martini, Y. Zhou, H. Sun, S. S. Shell

This study identifies transcription start sites and RNA cleavage sites in Mycobacterium smegmatis under aerobic growth and hypoxia, revealing regulatory mechanisms shared with Mycobacterium tuberculosis.

bioRxiv · Sep 23, 2018Microbiology