Adipose Triglyceride Lipase is needed for homeostatic control of Sterol Element-Binding Protein-1c driven lipogenesis
B. I. Wieser, P. Pena de la Sancha, S. Schauer, H. Reicher, W. Sattler, R. Breinbauer, M. Schweiger, P. J. Espenshade, R. Zechner, G. Hoefler, P. W. Vesely
This study shows that ATGL-derived unsaturated FAs suppress SREBP-1c activation, linking lipolysis and lipogenesis through an ATGL/SREBP-1c axis.
bioRxiv · Nov 2, 2020 · PreprintBiochemistry