Adenovirus type 34 and HVR1-deleted Adenovirus type 5 do not bind to PF4: clearing the path towards vectors without thrombosis risk
E. Sallard, D. Pembaur, K. Schroeer, S. Schellhorn, G. Koukou, N. Schmidt, W. Zhang, F. Kreppel, A. Ehrhardt
The paper identifies adenovirus types and modified vectors that do not bind to PF4, reducing thrombosis risk in vaccine development.
bioRxiv · Nov 7, 2022 · PreprintMicrobiology