Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC
B. J. Smith, C. Zhao, V. Dubinkina, X. Jin, L. Zahavi, S. Shoer, J. Moltzau-Anderson, E. Segal, K. Pollard
The paper introduces StrainPGC and MIDAS v3 to accurately estimate intraspecific microbial gene content variation in metagenomic data, outperforming existing methods and revealing functional diversity in gut microbiomes.
bioRxiv · Apr 10, 2024Microbiology