scAAVengr: Single-cell transcriptome-based quantification of engineered AAVs in non-human primate retina
B. E. Ozturk, M. E. Johnson, M. Kleyman, S. Turunc, J. He, S. Jabalameli, Z. Xi, M. Visel, V. L. Dufour, S. Iwabe, F. Pompeo Marinho, G. D. Aguirre, J.-A. Sahel, D. V. Schaffer, A. R. Pfenning, , L. C. Byrne
The paper develops scAAVengr, a single-cell pipeline to quantify AAV gene expression efficiency in non-human primate retina, demonstrating its utility with a top-performing AAV variant.
bioRxiv · Oct 1, 2020 · PreprintBioengineering