Cell BiologybioRxivPreprint
Activation of TPC2 amplifies lysosome-mitochondria calcium transfer to regulate energetic stress responses
Sadia Ahmed, Namratha Javvaji, Katherine L. Hammond…·Jillian N. Simon
This study shows TPC2 activation enhances lysosome-mitochondria calcium transfer, affecting mitochondrial function and stress responses, with implications for neuroprotection in stroke.