Author

Sam Natla

University of Michigan

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Genetics· 1

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Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amy Krans· 1 shared Brittany N. Flores· 1 shared Fang HeiD· 1 shared Michelle A. Frazer· 1 shared Olamide Adefioye· 1 shared Peter K. ToddiD· 1 shared Sami J. BarmadaiD· 1 shared Sarjina Niraula· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenetics

Amy Krans

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1 paper

Recent·Most cited

The carboxyl-termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD

Fang He, Brittany N. Flores, Amy Krans, Michelle A. Frazer, Sam Natla, Sarjina Niraula, Olamide Adefioye, Sami J. Barmada, Peter K. Todd

This paper shows that the carboxyl-termini of RAN translated DPRs from GGGGCC repeats affect toxicity in ALS/FTD models, with GR DPRs showing greater toxicity due to their unstructured C-termini.

Acta Neuropathologica Communications · Aug 4, 2020Peer-reviewedGenetics