GeneticsActa Neuropathologica CommunicationsPeer-reviewed
The carboxyl-termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD
Fang He, Brittany N. Flores, Amy Krans…·Peter K. Todd
This paper shows that the carboxyl-termini of RAN translated DPRs from GGGGCC repeats affect toxicity in ALS/FTD models, with GR DPRs showing greater toxicity due to their unstructured C-termini.
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