Lithium Chloride Inhibits Iron Dysregulation and Ferroptosis in Induced Pluripotent Stem Cells with ApoE4/E4 from a sporadic Alzheimer's disease patient
Ying Wang, Samuel Anchipolovsky, Piplu Bhuiyan, Luna Sato, Ge Liang, De‐Maw Chuang, Huafeng Wei
This study shows lithium chloride reduces iron dysregulation and ferroptosis in ApoE4/E4 iPSCs from a sporadic Alzheimer's patient, improving cell viability and mitochondrial function.
bioRxiv · Aug 28, 2025 · PreprintCell Biology