Ge Liang

Intranasal dantrolene nanoparticles inhibit lipopoly-saccharide-induced helplessness and anxiety be-havior in mice

This study shows intranasal dantrolene nanoparticles reduce LPS-induced anxiety and depression in mice by inhibiting inflammation and preserving synaptic proteins.

Lithium Chloride Inhibits Iron Dysregulation and Ferroptosis in Induced Pluripotent Stem Cells with ApoE4/E4 from a sporadic Alzheimer's disease patient

This study shows lithium chloride reduces iron dysregulation and ferroptosis in ApoE4/E4 iPSCs from a sporadic Alzheimer's patient, improving cell viability and mitochondrial function.

Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD mice

This study shows that intranasal lithium salt delivery in RFV reduces brain inflammation and pyroptosis, improves memory and depression-like behaviors in 5XFAD mice, with minimal side effects.

Intranasal dantrolene nanoparticles inhibit inflammatory pyroptosis in 5XFAD mice brains

This study shows that intranasal dantrolene nanoparticles reduce pyroptosis and inflammation in 5XFAD mice brains without affecting organ function or body weight.