Author

Sandra Le

Joslin Diabetes Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alejandro PenaiD· 1 shared Bofei YuiD· 1 shared Christopher Cahill· 1 shared Cristina Aguayo‐MazzucatoiD· 1 shared Denis WirtziD· 1 shared Duygu UcariD· 1 shared Dylan Baker· 1 shared Fan Wu· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Alejandro PenaORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Distinct senescent β-cell senotypes differentially drive islet aging and dysfunction

Kanako Iwasaki, Hui Pan, Jonathan M. Dreyfuss, Maya Jackson, Sergii Domanskyi, Dylan Baker, Priscila Carapeto, Christopher Cahill, Sandra Le, Francesko Hela, Juliana Alcoforado Diniz, Giray Naim Eryilmaz, Fan Wu, Pei-Hsun Wu, Bofei Yu, , Cristina Aguayo‐Mazzucato

The paper identifies two distinct senescent β-cell subpopulations with different functional roles in islet aging and dysfunction using single-cell proteomics and transcriptomics.

bioRxiv · May 28, 2026 · PreprintCell Biology