Author

Sara Bertelli

Humboldt-Universität zu BerlinPrimary ORCID profile (0000-0002-8662-7482 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Sara BertelliiD1 paper · Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Andrew J.R. PlestediD· 2 shared Alice PodestàiD· 1 shared Franziska Arnold· 1 shared Henrik AlleiD· 1 shared Holly J. Hughes· 1 shared Jörg RP GeigeriD· 1 shared Julia Arnold· 1 shared Julia OnkeniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Andrew J.R. PlestedORCID

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2 papers

Recent·Most cited

The polyamine naphthyl-acetyl spermine trihydrochloride (NASPM) lacks specificity for Ca2+-permeable AMPA receptors and suppresses seizure like activity in human brain tissue by inhibition of NMDA receptors.

Alice Podestà, Laura Monni, Franziska Arnold, Julia Arnold, Sara Bertelli, Ran Xu, Julia Onken, Ulrich‐Wilhelm Thomale, Thilo Kalbhenn, Matthias Simon, Thomas Sauvigny, Henrik Alle, Andrew J.R. Plested, Martin Holtkamp, Jörg RP Geiger, Pawel Fidzinski

This study shows NASPM inhibits NMDA receptors rather than CP-AMPARs in human brain tissue, challenging its use as a specific CP-AMPAR inhibitor and questioning its therapeutic potential.

bioRxiv · May 14, 2025 · PreprintNeuroscience

iGlu3Fast and iGlu3Slow, improved fluorescent reporters for detection of spontaneous glutamate activity in the brain

Oanh Tran, Sara Bertelli, Holly J. Hughes, Laura Rocha Llabrés, Tom D. Carter, Andrew J.R. Plested, Katalin Török

The paper introduces two improved fluorescent glutamate sensors, iGlu3Fast and iGlu3Slow, with distinct kinetic properties for imaging glutamate activity in the brain.

bioRxiv · Aug 30, 2024 · PreprintNeuroscience