Author

Sebastian Fernandez

University of California, Berkeley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:flow cytometry· 1 Assay:imaging· 1

Frequent Co-Authors

Daniel A. PortnoyiD· 2 shared Diego Gonzalez Ventura· 2 shared Jesse Garcia CastilloiD· 2 shared Julia Ybarra· 2 shared Michel J.P. DuPageiD· 2 shared Nicole Flores Hernandez· 2 shared Elina Wells· 1 shared Jacob T. Williams· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Daniel A. PortnoyORCID

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Author profile →

2 papers

Recent·Most cited

TLR2 signaling uniquely destabilizes tumor Tregs to promote cancer immunotherapy

Timothy F. Campbell, Jesse Garcia Castillo, Sebastian Fernandez, Diego Gonzalez Ventura, Jenna Vickery, Stefan Homentcovschi, Nicole Flores Hernandez, Julia Ybarra, Daniel A. Portnoy, Michel J.P. DuPage

This study shows that TLR2 signaling in innate immune cells within tumors reduces Treg stability, enhancing cancer immunotherapy by improving CD8+ T cell function.

bioRxiv · Jun 26, 2025 · PreprintImmunology

Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy

Jesse Garcia Castillo, Sebastian Fernandez, Timothy Campbell, Diego Gonzalez Ventura, Jacob T. Williams, Julia Ybarra, Nicole Flores Hernandez, Elina Wells, Daniel A. Portnoy, Michel J.P. DuPage

This study investigates how different routes of Listeria monocytogenes administration affect tumor growth in mice, finding that IV followed by IT administration controls tumor growth through anti-Lm CD8 T cells.

Immunity · Feb 20, 2024Peer-reviewedImmunology