Genome-wide CRISPR screen reveals PEX11B as a host restriction factor against ORFV through membrane fluidity regulation
Xiaoran Gao, Jinyang Hao, Sha Lu, Shida Wang, Yu Sun, Xin Ke, Xia Gao, Yuan Su, Yuze Sun, Yu Tian, Wenyu Yan, Jinliang Wang, Zhong Zheng, Rong Hai, Qianyi Zhang, , Guojun Wang
The paper identifies PEX11B as a host restriction factor against ORFV by showing its role in regulating membrane fluidity and peroxisomal integrity.
PLoS Pathogens · Jul 15, 2026Peer-reviewedMicrobiology