Author

Shanlan Mo

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Hao ZhangiD· 2 shared Zhen HeiD· 2 shared Zheng HuiD· 2 shared Aaron M. HorningiD· 1 shared Annika K K WeimeriD· 1 shared Anshul Bharat KundajeiD· 1 shared Aziz KhaniD· 1 shared Bahareh BahmaniiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Hao ZhangORCID

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2 papers

Recent·Most cited

Single-crypt evolutionary trajectories of human sporadic and hereditary colorectal precancers

Shanlan Mo, Duo Xie, Hao Zhang, Kun Wang, Juanzhen Tong, Li Fan, Daqi Deng, Jie Yu, Jing Yu, Zan Li, Leo T. O. Lee, Weiwei Zhai, Zhen He, Zheng Hu

This study compares the genomic evolution of sporadic and hereditary colorectal precancers using single-crypt whole-genome sequencing, revealing distinct mutation patterns and evolutionary trajectories.

bioRxiv · Apr 14, 2026 · PreprintCancer Biology

Polyclonal origins of human premalignant colorectal lesions

Debra Van Egeren, Ryan O. Schenck, Aziz Khan, Aaron M. Horning, Shanlan Mo, Clemens L. Weiß, Edward D. Esplin, Winston R. Becker, Si Wu, Casey Ryan Hanson, Nasim Bararpour, Lihua Jiang, Kévin Contrepois, Hayan Lee, Stephanie A. Nevins, , Christina N. Curtis

This study shows that many premalignant colorectal polyps contain multiple genetic lineages, indicating polyclonal origins rather than single-cell expansion.

Nature · Nov 25, 2025Peer-reviewedCancer Biology