Si Wu

This study shows that many premalignant colorectal polyps contain multiple genetic lineages, indicating polyclonal origins rather than single-cell expansion.

This study tracks microbiome changes across four body sites in 86 participants over six years, revealing site-specific stability, individualized dynamics, and altered patterns in insulin-resistant individuals.

Natural variation at KCS4 underlies differential accumulation of polyunsaturated triacylglycerols under carbon starvation by acting as a regulatory branch point in fatty acid fate.

This study profiles multi-omic changes in multiple tissues of rats during endurance exercise training, identifying molecular adaptations and sex-specific responses across time.

This paper introduces a statistical method to identify time intervals of temporal omics biomarkers in longitudinal studies, showing high specificity and sensitivity across simulated and real datasets.

metID automates compound annotation for LC-MS data by integrating multiple databases, improving efficiency and reproducibility.

The paper characterizes the dynamic multi-omic molecular response to acute exercise and identifies biomarkers of fitness.