Author

Shima Moradpour

SUNY Upstate Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4

Frequent Co-Authors

Gary C. T. ChaniD· 4 shared Brittany W. GeileriD· 2 shared Dilruba AkteriD· 2 shared Michael J. MilleriD· 2 shared Adam Tully WaickmaniD· 1 shared Ben B. Chauder· 1 shared Benjamin D. McElvanyiD· 1 shared C. S. C. HardyiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersMicrobiology

Gary C. T. ChanORCID

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Author profile →

4 papers

Recent·Most cited

Non-Canonical Activation of HSF1 Stimulates mTORC1-Mediated Translation in HCMV-Infected Monocytes

Michael J. Miller, Shima Moradpour, Brittany W. Geiler, Jamil Mahmud, Wayne A. Decatur, Gary C. T. Chan

This study shows HCMV activates HSF1 in monocytes to promote survival via mTORC1-mediated translation of pro-survival transcripts.

bioRxiv · Jul 23, 2026 · PreprintMicrobiology

Human cytomegalovirus triggered necroptosis is suppressed by sequestration of MLKL in the nucleus of infected monocytes

Brittany W. Geiler, Shima Moradpour, Ben B. Chauder, Dilruba Akter, Gary C. T. Chan

This paper shows HCMV extends monocyte lifespan by blocking apoptosis and triggering necroptosis, which it suppresses by sequestering MLKL in the nucleus.

Journal of Virology · Nov 5, 2025Peer-reviewedMicrobiology

B cell receptor dependent enhancement of dengue virus infection

Chad Gebo, C. S. C. Hardy, Benjamin D. McElvany, Nancy R. Graham, Joseph Q. Lu, Shima Moradpour, Jeffrey R. Currier, Heather Friberg, Gregory D. Gromowski, Stephen James Thomas, Gary C. T. Chan, Sean A. Diehl, Adam Tully Waickman

This study shows that DENV infection enhances B cells via their BCR, linking ADE potential to B cell susceptibility and highlighting B cells as a key reservoir in immune-mediated DENV enhancement.

PLoS Pathogens · Oct 31, 2024Peer-reviewedImmunology

Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo

Dilruba Akter, Juthi Biswas, Shima Moradpour, Meghan F Carter, Michael J. Miller, Dennis J. Thiele, Eain A. Murphy, Christine M. O'Connor, Jennifer F. Moffat, Gary C. T. Chan

Inhibiting HSF1 reduces HCMV replication in vitro and in vivo by targeting an early stage of the viral replication cycle.

Antiviral Research · Sep 23, 2024Peer-reviewedMicrobiology