Immune phenotype-guided identification of disease-associated pathobionts in Crohn's disease
Hiroko Nagao‐Kitamoto, Kohei Sugihara, Sho Kitamoto, Shinya Ebihara, Yeji Kim, Kira L. Newman, Uxía Alonso Alonso, Takehiro Suzuki, Yoshiyuki Kioi, Arash Yunesi, Naohiro Inohara, Christopher J. Alteri, Phillip Minar, Lee A. Denson, Peter Higgins, , Nobuhiko Kamada
This study identifies IL-1β-inducing pathobionts in Crohn's disease that drive inflammation and may predict response to anti-TNF therapies.
bioRxiv · Apr 1, 2025 · PreprintImmunology