Author

Sicheng Pang

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Mark W. GrinstaffiD· 2 shared Wilson W. WongiD· 2 shared Aidan T. RileyiD· 1 shared Alexander A. GreeniD· 1 shared Colin PorteriD· 1 shared Dana C. ShawiD· 1 shared Elijah Hammarlund· 1 shared Emily K. OsterweiliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Mark W. GrinstaffORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 30, 2025

Modified self-amplifying RNA mediates robust and prolonged gene expression in the mouse and ex vivo human brain

Jennifer Freire, Sicheng Pang, Joshua E. McGee…·Xue Han

This paper demonstrates that modified self-amplifying RNA (saRNA) enables long-lasting protein expression in mouse and human brain tissues.

1 citation

Synthetic BiologybioRxivPreprintJun 17, 2025

A Unified Framework for Model-Informed and Agentic RNA Design

Aidan T. Riley, McKayla Vlasity, Wyatt M. Becicka…·Alexander A. Green

This paper introduces a framework for model-informed mRNA design using integrated gradients and an agentic hypothesis engine, achieving improved in vivo expression.

2 citations

deep learningstatistical model