Author

Silja Malkewitz

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Asimina Kakale· 2 shared Caroline OspeltiD· 2 shared Adrian CiureaiD· 1 shared Alexandra A. KhmelevskayaiD· 1 shared Anastasiya BörschiD· 1 shared Andrea LaimbacheriD· 1 shared Andreas RammingiD· 1 shared Bojana Müller-DuroviciD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Asimina Kakale

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Metabolic-secretory decoupling defines a disease-intrinsic state in rheumatoid arthritis monocytes

Shao Thing Teoh, Silja Malkewitz, Cristian Iperi, Celia Makowiec, Asimina Kakale, S.M. Duphey, Anastasiya Börsch, Katarzyna Buczak, Witold Wolski, Ming Yang, Christian Frezza, Caroline Ospelt, Oliver Distler, Diego Kyburz, Bojana Müller-Durovic

The paper identifies a stable metabolic-secretory defect in RA monocytes across activation states using multi-omics analysis, linking reduced glycosylation to disease mechanisms.

bioRxiv · Apr 27, 2026 · PreprintImmunology

Disease-specific fibroblast-myeloid interactions in rheumatoid arthritis synovium

Alexandra A. Khmelevskaya, Katerina Apostolopoulou, Camino Calvo Cebrian, Ege Ezen, Melpomeni Toitou, Phatthamon Laphanuwat, Masoumeh Mirrahimi, Celina Geiß, Marija Lugar, Asimina Kakale, Silja Malkewitz, Andrea Laimbacher, Dimitris Konstantopoulos, Vagelis E. Rinotas, Marietta Armaka, , Caroline Ospelt

This study identifies disease-specific fibroblast-myeloid interactions in RA synovium, showing SPP1 signaling and fibroblast-myeloid-dendritic interactions drive RA inflammation by linking innate immunity to autoimmunity.

bioRxiv · Nov 17, 2025 · PreprintImmunology