Andreas Ramming

This study identifies disease-specific fibroblast-myeloid interactions in RA synovium, showing SPP1 signaling and fibroblast-myeloid-dendritic interactions drive RA inflammation by linking innate immunity to autoimmunity.

The paper identifies a unique myeloid precursor population that facilitates the spread of psoriatic inflammation from skin to joints, interacting with fibroblasts to regulate T cell IL-17 expression.

This study performs a GWAS meta-analysis of psoriasis, identifying 109 susceptibility loci, including 45 new ones, and highlights potential therapeutic targets and disease mechanisms.

This study identifies GDF15 as a mediator of inflammation-associated bone loss via a brain-bone axis, showing it induces bone loss through GFRAL receptor activation in the hindbrain.