Author

Sisu Han

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1

Frequent Co-Authors

Carol Janine SchuurmansiD· 4 shared Satoshi OkawaiD· 4 shared Ana-Maria OproescuiD· 3 shared Antonio del SoliD· 3 shared Dawn L. Zinyk· 3 shared Hussein GhazaleiD· 3 shared Lakshmy VasaniD· 3 shared Yacine Touahri· 3 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersDevelopmental Biology

Carol Janine SchuurmansORCID

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4 papers

Recent·Most cited

NEUROG2 regulates a human-specific neurodevelopmental gene regulatory program

Lakshmy Vasan, Vorapin Chinchalongporn, Fermisk Saleh, Dawn L. Zinyk, Cao Ke, Hamsini Suresh, Hussein Ghazale, Lauren Belfiore, Yacine Touahri, Ana-Maria Oproescu, Shruti B Patel, Matthew W Rozak, Yutaka Amemiya, Sisu Han, Alexandra Moffat, , Carol Janine Schuurmans

The paper identifies NEUROG2's role in regulating a human-specific gene regulatory program in neural progenitor cells through transcriptomic analysis of knock-in organoids.

Development · Dec 16, 2024Peer-reviewedDevelopmental Biology

Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling

Joseph Hanna, Yacine Touahri, Alissa Pak, Lauren Belfiore, Edwin van Oosten, Luke Ajay David, Sisu Han, Yaroslav Ilnytskyy, Igor Kovalchuk, Deborah Marie Kurrasch, Satoshi Okawa, Antonio del Sol, Robert A. Screaton, Isabelle Aubert, Carol Janine Schuurmans

The paper shows glycolytic flux promotes rod photoreceptor differentiation by regulating Wnt signaling in murine retinal progenitor cells.

bioRxiv · Jul 12, 2024Developmental Biology

Proneural genes form a combinatorial code to diversify neocortical neural progenitor cells

Alexandra Moffat, Ana-Maria Oproescu, Satoshi Okawa, Sisu Han, Lakshmy Vasan, Hussein Ghazale, Daniel J. Dennis, Dawn L. Zinyk, François Guillemot, Antonio del Sol, Carol Janine Schuurmans

The paper identifies a proneural gene combinatorial code that diversifies neocortical neural progenitor cells through gene regulatory networks and cell fate decisions.

bioRxiv · Jul 29, 2023 · PreprintDevelopmental Biology

Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding

Sisu Han, Satoshi Okawa, Grey Wilkinson, Hussein Ghazale, Lata Adnani, Rajiv Dixit, Lígia Tavares, Imrul Faisal, Matthew J. Brooks, Véronique Cortay, Dawn L. Zinyk, Adam Sivitilli, Saiqun Li, Faizan Malik, Yaroslav Ilnytskyy, , Carol Janine Schuurmans

The paper shows Neurog2 and Ascl1 genes regulate cortical progenitor differentiation and folding through Notch signaling in lissencephalic brains.

Neuron · Aug 17, 2021Peer-reviewedDevelopmental Biology