Author

Solange Sarkis

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Cécile DelettreiD· 2 shared Frédéric MichoniD· 2 shared Mélissa GirardiD· 2 shared Agnès Müller· 1 shared Alicia Caballero Megido· 1 shared Bianca Johansen· 1 shared Chantal Cazvieille· 1 shared Chloé ChamardiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Cécile DelettreORCID

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2 papers

Recent·Most cited

Pitx2-associated early-onset glaucoma alters corneal innervation and sensory function in a sex-specific manner

Solange Sarkis, Luna Dumon, Mélissa Girard, Chantal Cazvieille, Marina Schverer, Vincent Daïen, Bianca Johansen, Cécile Delettre, Chloé Chamard, Frédéric Michon

This study shows that Pitx2-associated glaucoma causes sex-specific changes in corneal nerve structure and sensory function, with females showing more inflammatory and stress-related changes than males.

bioRxiv · May 1, 2026 · PreprintNeuroscience

Inherited mitochondrial dysfunction triggered by OPA1 mutation impacts the sensory innervation fibre identity, functionality and regenerative potential in the cornea

Léna Meneux, Nadège Feret, Sarah Pernot, Mélissa Girard, Solange Sarkis, Alicia Caballero Megido, Mélanie Quilès, Agnès Müller, Laura Fichter, Jérôme Vialaret, Christophe Hirtz, Cécile Delettre, Frédéric Michon

This study shows that OPA1 mutation causes corneal innervation issues, including reduced sensitivity and impaired regeneration, despite normal epithelial function.

Scientific Reports · Aug 13, 2024Peer-reviewedPathology