Author

Stephane Angers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Traver HartiD· 2 shared Zachary SteinhartiD· 2 shared Benjamin J. Blencowe· 1 shared Carolyn L. CumminsiD· 1 shared ChangJiang Xu· 1 shared Danielle A. Bozek· 1 shared Debashish RayiD· 1 shared Emma Zilberman· 1 shared

Activity by Year

2015-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Traver HartORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The functional genomic circuitry of human glioblastoma stem cells

Graham MacLeod, Danielle A. Bozek, Nishani Rajakulendran, Vernon Monteiro, Moloud Ahmadi, Zachary Steinhart, Michelle M. Kushida, Helen Yu, Fiona J. Coutinho, Ian Restall, Xiaoguang Hao, Traver Hart, H. Artee Luchman, Samuel Weiss, Peter B. Dirks, Stephane Angers

This study uses CRISPR-Cas9 screens in patient-derived glioblastoma stem cells to identify essential genes and pathways for stemness and drug resistance, revealing new therapeutic targets.

bioRxiv · Jun 28, 2018 · PreprintCancer Biology

ARGLU1 is a Glucocorticoid Receptor Coactivator and Splicing Modulator Important in Stress Hormone Signaling and Brain Development

Lilia Magomedova, Jens Tiefenbach, Emma Zilberman, Veronique Voisin, Melanie Robitaille, Serge Gueroussov, Manuel Irimia, Debashish Ray, Rucha Patel, ChangJiang Xu, Pancharatnam Jeyasuria, Gary D. Bader, Timothy R. Hughes, Henry Krause, Benjamin J. Blencowe, , Carolyn L. Cummins

This study identifies ARGLU1 as a glucocorticoid receptor coactivator and splicing modulator, showing its role in stress hormone signaling and brain development through genetic and transcriptomic analyses.

bioRxiv · Aug 12, 2016Molecular Biology

Systematic discovery and classification of human cell line essential genes

Traver Hart, Megha Chandrashekhar, Michael Aregger, Zachary Steinhart, Kevin R. Brown, Stephane Angers, Jason Moffat

This study identifies and classifies human cell line essential genes using an optimized CRISPR-Cas9 screen, finding twice to thrice as many essential genes as previous RNAi studies.

bioRxiv · Feb 18, 2015 · PreprintGenomics