StJohn Townsend

Gene function and expression profiling in yeast spores, killifish diapause embryos, and their post-dormant offspring cells

The paper compares gene function and expression in dormant cells of yeast spores and killifish diapause embryos, finding conserved transcriptomic and proteomic changes across species.

Functional profiling of long intergenic non-coding RNAs in fission yeast

The paper functionally profiles long intergenic non-coding RNAs (lincRNAs) in fission yeast by analyzing mutant phenotypes across various conditions.

Barcode Sequencing and a High-throughput Assay for Chronological Lifespan Uncover Ageing-associated Genes in Fission Yeast

This study introduces improved methods for studying chronological lifespan in fission yeast, identifying new ageing-associated genes with potential relevance to human ageing.

C. elegans hermaphrodites undergo semelparous reproductive death

The paper shows that C. elegans hermaphrodites undergo reproductive death after reproduction, which is suppressed by germline removal and linked to lifespan extension.

C. elegans provide milk for their young

This study shows that C. elegans mothers transfer yolk to offspring via lactation, a process promoted by insulin/IGF-1 signalling, leading to reproductive death.

A natural variant of the sole pyruvate kinase of fission yeast lowers glycolytic flux triggering increased respiration and oxidative-stress resistance but decreased growth

The paper identifies a natural variant in fission yeast Pyk1 that reduces glycolytic flux, increases respiration, and enhances oxidative-stress resistance but decreases growth.