Beta human papillomavirus 8E6 promotes alternative end-joining
C. Hu, T. Bugbee, R. Palinski, I. Akinyemi, M. T. McIntosh, T. MacCarthy, S. Bhaduri-McIntosh, N. Wallace
This study shows HPV8 E6 promotes alternative end-joining (Alt-EJ) by interacting with p300, leading to increased genomic instability and deletions with Alt-EJ signatures.
bioRxiv · Jul 29, 2022Cancer Biology