Author

T. Fauti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Bacac· 2 shared A. B. Roth· 1 shared A. Freimoser-Grundschober· 1 shared A. M. Giusti· 1 shared A. Moisan· 1 shared A. Paehler· 1 shared A. Ruefli-Brasse· 1 shared A. Schneider· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

M. Bacac

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Human immunocompetent Organs-on-Chips platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

L. Cabon, D. Petropolis, W. Tien-Street, P. R. Ng, H. S. Grant, K. Karalis, G. A. Hamilton, J. Sam, T. Weinzierl, T. Fauti, A. Freimoser-Grundschober, J. Eckmann, C. Hage, M. Geiger, V. Micallef, , R. Barrile

The paper demonstrates that human immunocompetent Organs-on-Chips can predict safety liabilities of T-cell bispecific antibodies targeting tumor antigens.

bioRxiv · Feb 22, 2021Cancer Biology

BET Inhibition Enhances TNF Mediated Anti-Tumor Immunity

L. C. Wellinger, S. J. Hogg, D. M. Newman, T. Friess, D. Geiss, J. Michie, K. M. Ramsbottom, M. Bacac, T. Fauti, D. Marbach, L. Jarassier, P. Thienger, A. Paehler, L. A. Cluse, C. J. Kearney, , R. W. Johnstone

This paper identifies BET bromodomain inhibitors as agents that enhance anti-tumor immunity by sensitizing tumors to TNF-mediated cytotoxicity through suppression of NF-κB signaling.

bioRxiv · Feb 15, 2021Cancer Biology