Author

T. Fessl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:fluorescence / live-cell microscopy· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

I. Collinson· 2 shared R. Tuma· 2 shared S. E. Radford· 2 shared W. J. Allen· 2 shared D. W. Watkins· 1 shared D. Watkins· 1 shared J. A. Crossley· 1 shared J. Horne· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

I. Collinson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Energy landscape steering mediates dynamic coupling in ATP-driven protein translocation by the bacterial Sec machinery

J. A. Crossley, W. J. Allen, D. W. Watkins, T. Sabir, S. E. Radford, R. Tuma, I. Collinson, T. Fessl

This study uses single-molecule fluorescence to show that SecYEG dynamically couples with SecA through energy landscape steering, enhancing protein translocation efficiency.

bioRxiv · Jun 6, 2023 · PreprintBiophysics

Dynamic action of the Sec machinery during initiation, protein translocation and termination revealed by single molecule fluorescence

T. Fessl, D. Watkins, P. Oatley, W. J. Allen, R. A. Corey, J. Horne, S. A. Baldwin, S. E. Radford, I. Collinson, R. Tuma

This study uses single molecule FRET to analyze Sec machinery dynamics during protein translocation, revealing initiation, transport, and termination phases with specific roles for SecA and ATP hydrolysis.

bioRxiv · Jan 17, 2018Biophysics