The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways
R. Berkane, H. Ho-Xuan, M. Glogger, P. Sanz-Martinez, L. Brunello, T. Glaesner, S. K. Kuncha, K. Holzhueter, S. Cano-Franco, V. Buonomo, P. Cabrerizo-Poveda, A. Balakrishnan, M. Misra, T. Juretschke, K. Husnjak, , A. Stolz
This study identifies CK2-dependent phosphorylation and ubiquitination as essential for FAM134B and FAM134C-driven ER-phagy activation during mTOR inhibition.
bioRxiv · Feb 27, 2023Cell Biology