Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons
T. Grenier, J. Consuegra, M. Galvao Ferrarini, H. Akherraz, L. Bai, Y. Dusabyinema, I. Rahioui, P. da Silva, B. Gillet, S. Hughes, C. Ramos, R. Matos, F. Leulier
The paper shows that Lactiplantibacillus plantarum uses r/tRNA operons to communicate with Drosophila, activating GCN2 in enterocytes to promote systemic growth.
bioRxiv · Oct 31, 2021Microbiology